Widespread transfer of resistance genes between bacterial species in an intensive care unit: implications for hospital epidemiology.

نویسندگان

  • Nashwan Al Naiemi
  • Birgitta Duim
  • Paul H M Savelkoul
  • Lodewijk Spanjaard
  • Evert de Jonge
  • Aldert Bart
  • Christina M Vandenbroucke-Grauls
  • Menno D de Jong
چکیده

A transferable plasmid encoding SHV-12 extended-spectrum beta-lactamase, TEM-116, and aminoglycoside resistance was responsible for two sequential clonal outbreaks of Enterobacter cloacae and Acinetobacter baumannii bacteria. A similar plasmid was present among isolates of four different bacterial species. Recognition of plasmid transfer is crucial for control of outbreaks of multidrug-resistant nosocomial pathogens.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Carbapenem restriction and its Effect on Bacterial Resistance in an Intensive Care unit of a Teaching Hospital

Development of antibiotic resistance in Intensive Care Units (ICUs) is a worldwide problem. The purpose of this study was to evaluate the effect of an antibiotic stewardship program (ASP) by carbapenems restriction on gram-negative antimicrobial resistance in ICU. The study was designed in a 21 bedded general ICU of a teaching hospital with two wings (one and two) in Tehran, Iran. Carbapenem pr...

متن کامل

Carbapenem restriction and its Effect on Bacterial Resistance in an Intensive Care unit of a Teaching Hospital

Development of antibiotic resistance in Intensive Care Units (ICUs) is a worldwide problem. The purpose of this study was to evaluate the effect of an antibiotic stewardship program (ASP) by carbapenems restriction on gram-negative antimicrobial resistance in ICU. The study was designed in a 21 bedded general ICU of a teaching hospital with two wings (one and two) in Tehran, Iran. Carbapenem pr...

متن کامل

Study of Bacterial Contamination of Mobile Phones and Stethoscopes in Neonatal Intensive Care Unit

Mobile phones and stethoscopes used in neonatology units could be colonized by potentiel bacteria pathogens. It can be a vector of severe nosocomial infections and multi-drug-resistant pathogens. The aim of this study is to evaluate the microbial contamination of mobile phones and stethoscopes, used by medical and paramedical staff. The study was conducted in neonatal intensive care unit (NICU)...

متن کامل

Determination of Antibiotic Resistance Pattern of Bacteria Isolated from Blood, Cerebrospinal Fluid, and Urine Samples in Neonatal Intensive Care Unit of Ali Asghar Hospital, Iran during 2013-15

Background: Infections are one of the most important causes of death in infants, especially in developing countries. Inappropriate use and administration of antibiotics can contribute to the resistance and spread of infection. In this study, we determined the antibiotic resistance pattern of the bacteria isolated from clinical samples of blood, cerebrospinal fluid, and urine in the neonatal int...

متن کامل

Molecular detection of Integron genes and pattern of antibiotic resistance in Pseudomonas aeruginosa strains isolated from intensive care unit, Shahid Beheshti Hospital, North of Iran

Pseudomonas aeruginosa is one of the most important pathogens that causes nosocomial infections and shows high level of antibiotic resistance. Integrons are one of the transposable elements in bacteria and their role in antibiotic resistance has been well demonstrated. The aim of this study was a molecular characterization of the integron genes and the determination of the resistance or sensiti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of clinical microbiology

دوره 43 9  شماره 

صفحات  -

تاریخ انتشار 2005